Actovegin. Actovegin effects

Actovegin is one of the most widespread medicines for the treatment of cerebrovascular diseases and other health problems including even rheumatological diseases. Its effectiveness is related to its properties to restore the functional condition of different organs and systems. The effects of Actovegin are more expressed in hypoxic origin of the tissue's damage.  Depletion of energy resources leads to destruction of the cells membrane and cytolysis, accumulation of the lactic acid and tissue acidosis.

Actovegin effects:

1. Actovegin increases anaerobic breathing of the tissues which are in metabolic insufficienc
2. Actovegin's ingredients exert insulin action. In patients with insulin dependent diabetes Actovegin significantly reduces the progression of diabetic angiopathy.
3. Actovegin activates the metabolic processes in the organism
4. Actovegin exerts positive therapeutic effect in patients suffering from peripheral cerebrovascular disorders. This effect is related to enhancement of vascularization and development of collateral blood circulation
5. Actovegin exerts immune-modulating action.
6. Actovegin improves the supply of oxygen and decreases the expression of ischemic tissue damages, indirectly contributes to the synthesis of cell proteins.

Rheumatologists are interested in almost all of these Actovegin effects. As an important component in the therapy, Actovegin is used in rheumatoid arthritis, systemic lupus erythematosus, systemic sclerodermia and many other rheumatoid diseases. The medication improves the quality of life in patients with long-term cardiac defects and chronic heart failure.  Actovegin is available on the pharmaceutical market more than 10 years and for this period it proved its high efficiency and safety.

Actovegin - information for the specialists. The main pharmacological action of Actovegin consists in improvement of glucose transport to the tissues and enhancement of glucose metabolism. This leads to the activation the processes of anaerobic oxidation and increases energetic cell's potentional.

• Actovegin possesses the following functions:
• Actovegin increases ATP
• Actovegin activates the enzymes of oxidative phosphorylation
• Actovegin increases the activity of acidic phosphatase and lysosomal activity of the cells
  

Actovegin increases the amount of potassium ions in the cells, resulting in activation of potassium dependent enzymes such as catalase, saccharase, glucose oxidase.