of dutasteride and tamsulosin has been properly studied in patients with BPH and it was shown high effectiveness and safety profile. Dutasteride helps reduce the size of enlarged prostate gland. Tamsulosin lowers the tone of smooth muscles in the prostate gland,  prostatic urethra and urogenital passages. By relaxing smooth muscles, tamsulosin relives the symptoms of  obstruction and irritation associated with benign prostatic hyperplasia.  Vice president, R&D medicine development leader at Glaxo Smith Klein Anne Phillips shows that is the first time when dutasteride and tamsulosin will be available at one capsule. The drug is contraindicated for use in women and children, as well as patients with hypersensitivity to dutasteride or tamsulosin.

Dutaseride is currently available under the name Avodart and Tamsulosin under the name Flomax.

Glaxo Smith Klein expects that Jalyn (dutasteride 0.5 mg and tamsulosin 0.4 mg) will be available at the pharmaceutical market  during the second half of 2010.

Tamsulosin is currently marketed under the brand name Flomax.

Generic Tamsulosin is selective alpha-adrenergic blocker used to treat benign prostatic hyperplasia – one of the most common urological disease among men over 40 years of age.

Tamsulosin generic belongs to a group of medicines called alpha blockers. Action mechanism is associated with blocking alpha-1 receptors. Alpha-1 receptors are located in different organs and systems including blood vessels and prostate gland. By blocking Alpha-1 receptors tamsulosin helps to relax prostate gland muscles and bladder neck. This helps to relieve the symptoms of enlarge prostate.

The symptoms of benign prostatic hyperplasia include: frequent urination accompanied by a strong urge to urination, difficult urination, a feeling of incomplete emptying of the bladder, weak urine stream, frequent night urination. Tamsulosin can significantly improve the patient’s state.

This improvement has been usually observed within the first week and lasted throughout the study period (13 weeks).

This improvement was usually seen within the first week and lasted throughout the study period (13 weeks).
Tamsulosin is taken once daily 30 minutes after meal. The recommended dose varies from 0.4-0.8 mg, 30 minutes after eating.
The most common Tamsulosin side effects include: dizziness, headache, orthostatic hypotension, increased heart rate, rarely – retrograde ejaculation.