Green tea may slow the progression of chronic lymphocytic leukemia

Jun.17, 2010

The substance contained in green tea may become another tool for the treatment of patients with chronic lymphocytic leukemia (CLL). Researchers from the Mayo Clinic conduct the second phase of study of substance called epigallocatechin gallate (EGCG), also known as Epigallocatechin 3-gallate.

It is obvious that EGCG possess the ability to slow down the progression of lymphocytic leukemia. Clinical effectiveness of a substance is not very high, however statistically significant. The results suggest that EGCG can be successfully used in combination with other drugs at the early stages of lymphocytic leukemia.

The study involved 42 patients with chronic lymphocytic leukemia. All patients were at early stage of the disease. After the application of epigallocatechin gallate, the amount of leukemia cells are reduced by 20%. Nearly 70% of patients noticed decreasing the size of lymph nodes by 50%.

Apparently, the treatment with epigallocatechin gallate can not replace chemotherapy. However, the obtained results are very encouraging. Scientists plan to continue research to identify the maximum potential of the polyphenols in green tea.

The results will be presented at the annual meeting of the American Society of Clinical Oncology in Chicago.

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