Order Levitra online. Levitra drug

Drug name: Levitra
International nonproprietary name:  vardenafil

Pharmaceutical form:  coated tablets
Possible Levitra dosages: Levitra 5 mg, 10 mg and 20 mg.
Each tablet contains 5 mg, 10 mg or 20 mg Vardenafil
(5.926 mg, 11.852 mg or 23.705 mg Vardenafil hydrochloride trihydrate, respectively).

Levitra drug Pharmacological properties

Levitra drug pharmacodynamics

Erection is a hemodynamic process which is based on the relaxation of smooth muscles of cavernous body which are located in its arterioles. During sexual stimulation nitrogen oxide is released out of the nerve endings of activating the enzyme guanylate cyclase. This leads to increased amount of cyclic guanosine monophosphate (cGMP) of the corpus cavernosum. This results is relaxation of smooth muscles of the corpus cavernosum and increases blood flow to the penis.

By blocking specific phosphodiesterase type  5 (PDE5)  Levitra drug enhances the local action of endogenous nitric oxide (N0) in the cavernous body during the sexual stimulation. This ultimately causes a strong erection.

Levitra drug Pharmacokinetics

After oral administration Levitra drug is quickly absorbed and starts working within 15 minutes (in the majority of men after 25 minutes), duration of action is 4-5 hours.

Levitra drug uses

Levitra drug is indicated for the treatment of erectile dysfunction (inability to achieve and maintain an erection necessary for satisfactory sexual intercourse).

Levitra drug contraindications

• Hypersensitivity to any components of the drug.
• Severe cardiovascular diseases
• Severe liver or kidney diseases
• Concomitant use with nitrates or drugs, which are nitric oxide donators.
• The combination of HIV protease inhibitors such as indinavir or ritonavir.
• Levitra is not indicated for women and children under 16 years of age.
  

Levitra drug should be taken with caution should in patients:
With prolonged QT interval

• With anatomical deformation of the penis (cavernous fibrosis, Peyronie's disease);
• With diseases predisposing to priapism (sickle-cell anemia, multiple myeloma, leukemia);
• With severe hepatic impairment. In Patients with mild hepatic impairment the correction of dose is not required. In patients with moderate hepatic impairment initial dose is 5 mg per day. In future, depending on the efficacy and tolerability of treatment the dose of Levitra drug can be increased up to   10 mg;
• With kidney disease

•  With arterial hypotension (systolic blood pressure lower than 90 mm Hg)
•  With the recent stroke and myocardial infarction, with unstable angina;
•  With hereditary degenerative diseases of the retina (eg retinitis pigmentosa);
•  With a tendency to bleeding and exacerbation of peptic ulcer;
•  With aortic stenosis and idiopathic hypertrophic subaortal stenosis.
  

Levitra drug Dosing and Administration
The initial dose of Levitra drug is 10 mg.
You should take Levitra 25-60 minutes before sexual intercourse.
Levitra drug's duration of action is 4-5 hours.
The maximum recommended frequency of administration of the drug - 1 times per day. Depending on the efficacy and tolerability of treatment the dose of Levitra drug can be increased to 20 mg or decreased to 5 mg per day. The maximum recommended dose is 20 mg 1 time per day.  The dose 5mg of Levitra drug is recommended for older patients (over 65 years of age).
The dose 20mg is indicated in severe erectile dysfunction ( in patients with diabetes, prostatectomy), when the beginning dose of 10 mg is not enough effective. You can take Levitra drug with or without food. Levitra drug is effective only if you have a sexual excitement (sexual stimulation).

Levitra drug side effects

Levitra drug is generally well tolerated and Levitra side effects are usually mild and moderate.
The most observed Levitra side effects include (1-10%): headache, facial flushing, indigestion, nausea, dizziness, rhinitis.
Rare Levitra side effects include: (0,1-1%): facial swelling, photosensitivity, low back pain, hypertension, changes in functional "liver" tests, increased GGTP, increased levels of creatine kinase, myalgia, drowsiness, dyspnea, blurred vision, watery eyes , priapism, anaphylactic reaction (including laryngeal edema), angina pectoris, hypotension, myocardial ischemia, postural hypotension, syncopal states, increased muscle tone, nasal bleeding, glaucoma.

Levitra drug overdose

There is known cases of receiving Levitra dose 80 mg per day, which is not accompanied by the development of serious adverse reactions. However, at the same time when used in a dose of 40 mg Levitra can cause severe back pain and other most common Levitra side effects.

Levitra drug interactions

The dose of Levitra should not exceed 5 mg when it is used in combination with erythromycin, ketoconazole, itraconazole. The dose of ketoconazole and itraconazole at the same time should not exceed 200 mg. Combination with indinavir and ritonavir is contraindicated.

Nitrate, donator of nitric oxide. Concomitant application of Levitra and nitrates is contraindicated because of the risk of arterial hypotension.

A combination of alpha-adrenergic drugs and Levitra can be accompanied by the development of arterial hypotension. Levitra should be taken no earlier than 6 hours after administration of alpha-adrenergic blockers, and the dose should not exceed 5 mg.

Levitra drug - Frequently asked questions

Can you take Levitra with Cialis?

No. You should not take Levitra in with Cialis. The effectiveness and safety of this combination was not studied. That is why is it is not recommended to take Levitra with Cialis.

Where to purchase generic form of Levitra ?

You can purchase generic form of Levitra at our online pharmacy. We offer excellent prices and your satisfaction is guaranteed.

Viagra Cialis Levitra - which is the best?

All of these 3 medications are effective. However, the efficacy and tolerability varies from patient to patient. You can try 3 of these medications and choose the most appropriate for you. In addition, Levitra is usually better tolerable and Levitra side effects are less common.

How can order Levitra online?

You can order Levitra online using your Visa/Visa Electron. We provide secure and safe processing. The medicines will be shipped via EMS and registered air mail.

Which is Levitra effectiveness?

Levitra is effective in most of patients (nearly 90% of patients with moderate erectile dysfunction). Levitra does not work without sexual stimulation (sexual excitement).

Cialis vs Levitra?

There are some differences between Cialis and Levitra. Cialis works for 48 hours. Levitra works only for 4-5 hours in most of men. Levitra is more active than Cialis and is considered more tolerable than Cialis.