Diovan. New approach in high blood pressure treatment.
Date: Sunday 18 October, 2009
High blood pressure also called hypertension is one of the most widely-spread cardiovascular diseases. Currently more than 80 millions in the USA experience this conditions. However, not all of them receive appropriate treatment. As a result, each year thousands of people die because of heart attacks, strokes, heart failure and kidney damage.
In many cases all of these mentioned diseases are encouraged by high blood pressure. It is not secret that nowadays hypertension can be successfully treated by medicines and life style changes. Pharmaceutical industry has invented a lot of medicines that can successfully control blood pressure. Unfortunately, hypertension is not curable and patents have to take drugs the whole life. In this situation it's very important to choose the most effective and less dangerous for the health preparations. In this article we would like to talk about new hypertension pills known as Diovan.
Diovan®(valsartan) is a new generation hypertensive drug, that was created to provide patients with better hypotension effect and low frequency of side effects. Diovan combines with high clinical efficiency, excellent tolerability, usability and lack of significant interactions with other medicines. Diovan can worthily be considered a drug of choice in treatment of high blood pressure.
Why more and more health care providers give prominence to Diovan among all hypertensive drugs? Let's try to clear up.
Diovan belongs to the new generation anti-hypertensive remedies called angiotensin II receptor blockers. It works by inhibiting cardiovascular effects of angiotensin II through the selective blockage of AT1 receptors. This results in effective lowering of systolic and diastolic blood pressure.
When Diovan is absorbed into the blood circulation, it acts directly on AT1 receptors being in unchanged form. Only a small amount of Diovan is metabolized, the main part is excreted in native state. This allows Diovan to exert therapeutic effect in 2 hours after the application. Having a good pharmacokinetic indexes, the drug can be easily dosed.
Talking about safety and drug tolerance, it is necessary to underline that Diovan is well tolerated in a short and prolonged therapy. High Diovan safety is proved in patients with heart failure, essential hypertension, kidney failure, stenosis of the kidney's arteries, liver diseases and glaucoma. According to clinical data Diovan does not cause dose-dependent side effects, and is well-tolerated even in doses of 320mg. Good Diovan tolerability doesn't depend on age and sex. Thus, it's not necessary to correct dosage regimen in elderly people, patents with moderate kidney failure, unsevere liver disease of nonbiliary origin.
In conclusion, we would like to point on the most expressed Diovan characteristics and advantages in comparison with other anti-hypertensive drugs:
Diovan is highly selective:
- The drug controls blood pressure through selective block of AT1 receptors
- Diovan does not act on other enzymes including AT2
Diovan is highly effective:
- The drug possesses high clinical and therapeutic effect independently on age and sex. Diovan tolerance is the same as placebo:
- Excellent drug tolerability
- Therapy with Diovan doesn't require to monitor laboratory indexes
Diovan is easy in use:
- The drug controls blood pressure within 24 hours after the apllication
- Diovan has a good pharmacokinetic characteristic
- Therapeutic dose for the majority of patients is 80mg(1 tablet) per day
Finally we should mention that Diovan is RX drug meaning that you need a prescription to begin therapy. Never treat yourself by your own. Necessarily consult your doctor to specify the right dosage for you before the treatment.