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Vardenafil - generic made by Sunrise remedies or Centurion Laboratories What is Vardenafil? Vardenafil is international non proprietary name of a well known medication used for erectile dysfunction Vardenafil. Original Vardenafil is made by Bayer, generic Vardenafil (vardenafil hcl) is made by different manufacturers such as Aurochem, Cipla, Ranbaxy and Sunrise remedies. How does Vardenafil hcl acts? Vardenafil hcl belongs to a class of medications called PDE5 inhibitors. Physiological process of erection consists in release of nitrogen oxide in the cavernous body in response to sexual stimulation. Nitrogen oxide binds to guanylate cyclase and, thus, increases the amount of cyclic Cyclic guanosine monophosphate. This leads to relaxation of the smooth muscles of the cavernous body and increase of blood flow to the penis. Vardenafil hcl acts by inhibiting the enzyme PDE type 5 which breaks down cyclic GMP. In this way Vardenafil hcl increases the amount of Cyclic guanosine monophosphate and therefore blood flow to the penis. This ultimately leads to a strong erection. Vardenafil hcl uses Generic Vardenafil is used for the treatment of erectile dysfunction in men over 18 years of age. Erectile dysfunction is manifested in inability to achieve and maintain erection satisfactory for the sexual intercourse. Vardenafl hcl does not works without sexual excitement. The medication is effective in patients with diabetes, high blood pressure, high cholesterol. Vardenafil hcl 20mg tablets can be useful both for men who need some little help from time to time and for those ones who require serious treatment (men with severe erectile dysfunction). Vardenafil hcl tablets can be safely taken along with other common medications, but we do suggest people to consult with their personal doctors prior to taking Vardenafil hcl 20mg tablets. How Vardenafil is taken? Vardenafil tablets are taken orally. You can take tablets with our without food. The recommended doe Inside. Vardenafil can be taken irrespective of meals. The recommended dose of Vardenafil hcl is 10mg once daily 25-60 minutes before sexual intercourse. Vardenafil action lasts nearly 5-6 hours. Patients taking other medications or conditions involving reduced metabolism of vardenafil, the dose of generic Vardenafilshould be not more than 2,5-5 mg. Vardenafil dose of 5 mg is recommended for patients over 65 years of age. Then the dose can be increased to 10mg depending on the efficacy and tolerability. The starting dose of generic Vardenafil should be 5 mg daily in patients with moderate hepatic impairment. Do not take generic Vardenafilmore than once a day. The maximum recommended dose is 20 mg once daily. When Vardenafil hcl should not be taken? In case a person is using a nitrate drug for heart problems or chest pain, generic Vardenafil should not be taken. Among such medications are: Nitro-Dur, Nitrolingual, Nitrostat etc. Taking Vardenafil in combination with nitrate drugs may lead to a serious blood pressure drop which may result in severe hypovolemia, fainting. If you experience any of the following symptoms during sexual act, consult your doctor immediately: dizziness, nausea, pain, tingling in chest, muscle pain, joint pain. If the erection is painful or lasts more than 4 hours, it is necessary to consult your doctor. Prolonged erection can cause damage of penis (necrosis of the penile tissue). Vardenafil hci should not be taken in the following health problems: recent heart attacks or strokes in recent 6 months, extremely low blood pressure, extremely high blood pressure, unstable stenocardia, prolonged QT interval, aortal stenosis, leukemia, multiple myelomoma, liver failure Vardenafil drug should not be taken in diseases which predispose to priapism, anatomical deformation of the penis, tendency to bleedings, aggravation of stomach and duodenal ulcers Vardenafil hci is contraindicated for use in women and adolescents under 18 years of age. Make sure to consult your doctor of you take HIV medicines like protease inhibitors like indinavir or ritonavir. Which Vardenafil hcl side effects are possible? Vardenafil is well tolerated and side effects are usually insignificant and do not require the cessation of therapy. During clinical trials there were reported the following side effects:
How Vardenafil can interact with other medicines? Vardenafil is metabolized primarily in the live via isoenzymes of cytochrome P450, in particular - CYP3A4, as well as with some participation isozymes CYP3A5 and CYP2C9. Some medicines may affect the metabolism of generic Vardenafil. For example, for patients taking cimetidine, ketoconazole, itraconazole, indinavir or ritonavir, the maximum dose of Vardenafil should not exceed 5 mg. The dose of ketoconazole and itraconazole at the same time should not exceed 200 mg once daily. In concomitant application with the CYP3A4 inhibitor erythromycin the dose of Vardenafil should not exceed 10mg once daily. Avoid simultaneous use of generic Vardenafil with nitrates (such as nitroglycerin, sodium nitroprusside) or alpha-adrenergic blockers (drugs for the treatment of benign prostatic hyperplasia and / or lowering blood pressure). Concomitant application may result in drop in blood pressure and collapse. Since PDE inhibitors affect the system of nitric oxide / cGMP, PDE5 inhibitors may increase the hypotensive effects of nitrates. Generic Vardenafil should be taken not earlier than 6 hours after taking alpha-adrenergic blockers, and the dose should not exceed 5 mg once daily. In simultaneous use of generic Vardenafil with glyburide, nifedipine, warfarin, and digoxin were observed significant changes in pharmacokinetics. In simultaneous use of Vardenafil with warfarin was not observed changes in prothrombin time and clotting factors. In simultaneous use of Vardenafil HCI with acetylsalicylic acid, antacids, ACE inhibitors (enalapril, captopril), beta-blockers (propranolol, atenolol, metoprolol and others), diuretics, hypoglycemic agents (metformin and sulfonylurea derivatives), as well as with histamine H2-blockers receptors ranitidine and cimetidine changes in pharmacokinetic parameters were not observed. In studies in humans, while the application Vardenafil (vardenafil) with acetylsalicylic acid was not observed changes in bleeding time. There were not observed any changes while concomitant application with acetylsalicylic acid. As the safety and efficacy of combinations of Vardenafil with other agents for the treatment of erectile function (sildenafil, tadalafil) has not been investigated, the use of such combinations is not recommended. What happens if I miss a dose of Vardenafil HCL? Vardenafil hcl is taken when is needed. Usually there is not any scheme of therapy and schedule when you should take Vardenafil tablets. What happened if I take more than 20mg once daily? There are known cases of overdose of Vardenafil at a dose Vardenafil 40mg, 80mg, and even 160 mg. The symptoms of overdose included stomach pain, blurred vision, dyspepsia, muscle pain, priapism, back pain. Seek immediate medical attention if you took the dose of Vardenafil higher than recommended.
Vardenafil - Frequently asked questions
How much does Vardenafil cost? The price for Vardenafil 20mg N60 is 109.99$ The medication is made by Sunrise remedies - a well known manufacturer. Is Vardenafil made by Aurochem, Cipla, Ranbaxy, Sunrise remedies good? All of these manufacturers produce only effective and safe medicines. The quality of drugs corresponds to GMP standards. Where can I purchase Vardenafil online? You can purchase Vardenafil online at our online pharmacy. We can offer low prices and high quality of our medicines. How can I purchase Vardenafil online? You can purchase Vardenafil online using your Visa card? Do I need a prescription to purchase Vardenafil online? Yes. After placing an order you should send us a prescription. If you do not have a prescription please contact our customer support for additional information. Which are other uses of Vardenafil? Vardenafil is used only for erectile dysfunction. The effectiveness of Vardenafil for other health problems was not studied. Vitamins supplements and Vardenafil - what should I expect? You can take vitamin supplements with Vardenafil without any problems. However, if you notice any changes in your health while taking Vardenafil with vitamin supplements please inform your health care provider. Where can I get information about generic drug Vardenafil? You can get more information about generic drug Vardenafil at our website. If you didn't find the needed information please consult our pharmacists.