Title: Generic Alli. Buy Alli online. Alli side effects
What is generic Alli (orlistat)?
Generic Alli (Orlistat) is over-the-counter medication approved for weight loss and obesity treatment. It belongs to a group of specific inhibitors of gastrointestinal lipases. Orlistat works by reducing the amount of calories which human organism receives with food. Alli capsules helps to decrease excessive body weight by increasing the elimination of lipids with faeces. Generic Alli Orlistat is indicated for the treatment of obesity and overweight in combination with healthy foods and physical exercises.
Alli (orlistat) belongs to a group of specific inhibitor of gastrointestinal lipases. Orlistat exerts its therapeutic action in the stomach and bowel. The action mechanism of Alli is associated with formation of covalent bonds with the active serine parts of gastric and pancreatic lipases. Inactivated ferments lose the ability to break down lipids entering in the form of triglycerides and monoglycerides, fatty acids. As a result Alli lowers the number of calories receiving with food (unsplit triglycerides are not absorbed in the blood circulation). Because less calories comes with food Alli helps to decrease excessive body weight.
Alli oral exerts its therapeutic action without absorption into the systemic circulation.
Xenical increases the concentration of fat in the stool in 24-48 hours after oral administration.
When generic Alli is prescribed?
Generic Alli is licensed to treat overweight and obesity in patients with Body Mass Index higher than 29. Orlistat oral is used only in combination with weight loss programs such as appropriate diet and moderate physical exercises.
Which is Alli capsules pharmacokinetics?
Orlistat oral acts only in the stomach and bowel. Orlistat is not absorbed into the systemic blood circulation. Xenical is eliminated with faeces. A small amount of orlistat is excreted with urine.
How generic Alli is taken?
The recommended dose of Alli oral is one capsule 60 mg with fat meal. Alli should be taken during the meal or not later than 1 hour after meal. If a patient eats low lipid food, Orlistat dosage can be missed.
A patient should receive a balanced, moderately hypocaloric diet containing no more than 30% of lipids. Increasing the dose of Alli generic over the recommended (120 mg 3 times a day) does not lead to increase in its therapeutic effect. The action of Alli oral oral in patients with liver or kidney disease and in children has not been studied.
When Orlistat is contraindicated?
Orlistat oral is contraindicated in the following conditions:
· Reactions of hypersensitivity to Orlistat or other compounds of the medication
· Organs transplantation
· Overeating
· Thyroid problems
· Diabetes type 2 or type 1
· Malabsorption syndrome
· Urolithiasis (kidney stones)
· Pancreas problems
· Gall bladder diseases
· Children and adolescents under 18 years of age
Generic Alli is not recommended for use in pregnant and breastfeeding mothers. The effectiveness and safety of the medication in pregnant women was not studied. Generic Alli is a pregnancy category B meaning that effectiveness and safety of the drug was not studied properly in pregnant women.
Alli side effects
According to clinical studies the most common Alli side effects manifest in the form of gastrointestinal disorders and are related to action mechanism of the medication.
The most common Alli side effects include oily discharge from the rectum, meteorism with a certain amount of discharge, frequent urge to defecation, steatorrhea, increased frequency of defecation and fecal incontinence. Typically, these adverse reactions are transient.
Other Alli side effects include: stomach pain or discomfort, bloating, soft stools, abdominal pain or discomfort in the rectum, teeth and gum damage.
There were described hypersensitivity reactions such as of itching, rash, urticaria, angioedema and anaphylaxis.
In very rare cases there were observed infections of the upper or lower respiratory infections, flu, headaches, dysmenorrhea, anxiety, fatigue, urinary tract infections.
A lot of Orlistat side effects can be avoided by decreasing the consumption of fats with food.
In general the most common Alli side effects include:
· Stomach pain
· Fecal urgency
· Meteorism
· Anal oil seepage
· Oily stool
· Sinus infection
· Diarrhea
The frequency of Alli side effects can be avoided by decreasing the consumption of foods reach in fats (lipids)
Alli overdose
There are no reported any Alli overdose symptoms. Orlistat overdose symptoms are similar to common Alli side effects such as oily spotting, abdominal discomfort, fatty stool and others.
A lot of Orlistat side effects can be avoided by decreasing the consumption of fats with food.
Alli special cautions and precautions
Patients should be informed of the possibility of adverse reactions from the gastrointestinal tract and to learn how to eliminate them through better compliance with the diet, especially as regards the amount of fat contained in it. Patients should be encouraged to diet, because the chance of adverse reactions from the gastrointestinal tract may increase if Alli oral is taken with food reach in fats (eg, 2000 kcal daily, the amount of fats is more than 30%, which equals to 67 grams of fat ). The use of low-fat diet reduces the likelihood of side effects from the gastrointestinal tract. The medication can reduce absorption of fat-soluble vitamins such vitamin A, D, E, K. It is recommended to take multivitamin supplements while the treatment with the medication.
If multivitamins are taken, it is better to take no less than 2 hours after taking Alli, or before bedtime.
Safety and efficacy of Alli in patients with impaired hepatic function and / or kidney has not been established. Safety of the medication in children has not been established.
How Orlistat can interact with other medicines?
Orlistat capsules may interact with the following medicines:
· Amidoarone (Cordarone) - used for arrhythmia treatment. Orlistat may change to absorption of Amiodarine into the blood circulation
· Cyclosporine which is immunosuppressors. Orlistat reduces the absorption of cyslosporine making the medication less effective
· Diabetes medications. In patients with diabetes which lose weight the dose of anti-diabetic medicines should be adjusted.
· Alli can make reduce thyroid function causing hypothyroidism
· Fat soluble vitamins A, D, E, K. Orlistat can decrease the absorption of fat soluble vitamins.
How the medication should be stored?
Orlistat capsules should be stored at dry and protected from light place out of reach of children. Do not store orlistat oral in the bathroom.
Do I need a prescription to buy Alli online?
No. For generic Orlistat our online pharmacy does not require a prescription.
Where can I buy Alli online?
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Which is the manufacturer of Alli? The medication is made by Biocon Limited.
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