Generic Xenical. Order Xenical online. Orlistat
What is Xenical (orlistat)?
Generic Xenical is a powerful and specific inhibitor of gastrointestinal lipases. Orlistat reduces the amount of calories entering the organism. This helps to reduce excessive weight loss. Generic Xenical is indicated for the treatment of obesity and overweight in combination with healthy diet and moderate physical exercises.
Xenical (orlistat) is a powerful and specific inhibitor of gastrointestinal lipases. Therapeutic effect of Orlistat oral is manifested in the stomach and small intestine. The action mechanism of Xenical is related to formation of covalent bond with the active serine site of gastric and pancreatic lipases. Inactivated enzyme loses the ability to break down lipids coming in the form of triglycerides, fatty acids and monoglycerides. As a result the medication decreases the number of calories entering the organism (unsplit triglycerides are not absorbed in the blood circulation). This helps to decrease body weight.
Xenical oral exerts its therapeutic action without absorption into the systemic circulation.
Xenical increases the concentration of fat in the stool in 24-48 hours after administration.
When generic Xenical is prescribed?
Generic Xenical is prescribed for the treatment of overweight and obesity in patients with BMI higher than 29. Orlistat oral is used only in combination with weight loss programs such as healthy diet and moderate physical exercises.
Which is Xenical pharmacokinetics?
Orlistat oral acts only in the stomach and intestine. Orlistat is not absorbed into the blood circulation. Xenical is eliminated with faeces.
How generic Xenical is taken?
The recommended dose of Xenical generic is one capsule 120 mg with fat meal. Xenical should be taken during the meal or not later than 1 hour after meal. If a patient eats low lipid food, Orlistat dosage can be missed.
A patient should receive a balanced, moderately hypocaloric diet containing no more than 30% of fats. Increasing the dose of Xenical over the recommended (120 mg 3 times a day) does not lead to increase its therapeutic effect. The action of Xenical oral in patients with liver or kidney disease and in children has not been studied.
When Orlistat is contraindicated?
Orlistat oral is contraindicated in the following conditions:
· Known allergic reactions to Orlistat or other components of the medication
· Transplantation of the organs
· Bulimia
· Diseases of the thyroid gland
· Diabetes mellitus
· Malabsorption syndrome
· Urolithiasis
· Diseases of the pancreas
· Cholesthasis
· Children and adolescents under 18 years of age
Generic Xenical is not recommended for use in pregnant and breastfeeding mothers. The effectiveness and safety of the medication in pregnant women was not studied.
Generic Xenical side effects
According to clinical studies the most common Xenical side effects manifest in the form of gastrointestinal disorders and are related to action mechanism of the medication.
The most common Orlistat side effects include oily discharge from the rectum, meteorism with a certain amount of discharge, frequent urge to defecation, steatorrhea, increased frequency of defecation and fecal incontinence. Typically, these adverse reactions are transient.
Other Xenical side effects include: stomach pain or discomfort, bloating, soft stools, abdominal pain or discomfort in the rectum, teeth and gum damage.
There were described hypersensitivity reactions such as of itching, rash, urticaria, angioedema and anaphylaxis.
In very rare cases there were observed infections of the upper or lower respiratory infections, flu, headaches, dysmenorrhea, anxiety, fatigue, urinary tract infections.
A lot of Orlistat side effects can be avoided by decreasing the consumption of fats with food.
Xenical overdose
There are no reported any Xenical generic overdose symptoms. Orlistat overdose symptoms are similar to common Orlistat capsules side effects such as oily spotting, abdominal discomfort, fatty stool and others.
A lot of Orlistat side effects can be avoided by decreasing the consumption of fats with food.
Generic Xenical special cautions and precautions
Patients should be informed of the possibility of adverse reactions from the gastrointestinal tract and to learn how to eliminate them through better compliance with the diet, especially as regards the amount of fat contained in it. Patients should be encouraged to diet, because the chance of adverse reactions from the gastrointestinal tract may increase if Xenical oral is taken with food reach in fats (eg, 2000 kcal daily, the amount of fats is more than 30%, which equals to 67 grams of fat ). The use of low-fat diet reduces the likelihood of side effects from the gastrointestinal tract. The medication can reduce absorption of fat-soluble vitamins such vitamin A, D, E, K. It is recommended to take multivitamin supplements while the treatment with the medication.
If multivitamins are taken, it is better to take no less than 2 hours after taking generic Xenical, or before bedtime.
Safety and efficacy of Xenical in patients with impaired hepatic function and / or kidney has not been established. Safety of the medication in children has not been established.
How Orlistat can interact with other medicines?
Orlistat capsules may interact with the following medicines:
· Amidoarone (Cordarone) - used for arrhythmia treatment. Orlistat may change to absorption of Amiodarine into the blood circulation
· Cyclosporine which is immunosuppressors. Orlistat reduces the absorption of cyslosporine making the medication less effective
· Diabetes medications. In patients with diabetes which lose weight the dose of anti-diabetic medicines should be adjusted.
· Xenical can make reduce thyroid function causing hypothyroidism
· Fat soluble vitamins A, D, E, K. Orlistat can decrease the absorption of fat soluble vitamins.
How the medication should be stored?
Orlistat capsules should be stored at dry and protected from light place out of reach of children. Do not store orlistat oral in the bathroom.
Do I need a prescription to buy Xenical online?
No. For generic Xenical our online pharmacy does not require a prescription.
Where can I order Xenical online?
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How can I order Xenical online?
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Which is the manufacturer of Xenical?
The medication is made by Intas Pharmaceutical.
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